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The objective of the “Design Guide for Improving Hospital Safety in Earthquakes, Floods, and High Winds” is to inform and assist design professionals, hospital administrators, and facility managers in implementing sound mitigation measures that will decrease the vulnerability of hospitals to disruptions caused by natural hazard events. The intent of the Design Guide is to provide its audience with state-of-the-art knowledge on the variety of vulnerabilities faced by hospitals exposed to earthquakes, flooding, and high-winds risks, as well as the best ways to mitigate the risk of damage and disruption of hospital operations caused by these events.